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MiR-21 is targeted by STAT5 but dispensable for mammary gland development


ABSTRACT: In this study we identifies miR-21 to by under cytokine control through the transcription factor STAT5 and while miR-21 is differentially expressed during mammary gland development, miR-21 is dispensable for mammary development and lactation. We refer to wild-type mice (+/+) as WT and to mice lacking the mir-21 (-/-) as KO mice.

SUBMITTER: Keunsoo Kang 

PROVIDER: E-GEOD-50068 | BioStudies | 2013-08-22

SECONDARY ACCESSION(S): SRP028970

REPOSITORIES: biostudies

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