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Actively translating transcriptome (Ribotag) profiling of mouse retinal endothelial cells during postnatal development


ABSTRACT: Angiogenesis, a process mediating the expansion of vascular beds in many physiological and pathological settings, requires dynamic changes in endothelial cell (EC) behavior. The molecular mechanisms governing EC activity during different phases of vascular growth, remodeling, maturation, and quiescence remain elusive. Here, we have employed actively translating transcriptome analysis of mouse retinal ECs for the characterization of dynamic gene expression changes during postnatal development and the identification of critical angiogenic factors.

ORGANISM(S): Mus musculus

PROVIDER: E-MTAB-5087 | BioStudies |

REPOSITORIES: biostudies

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