Unknown

Dataset Information

0

The inhibition of enzymes by beryllium.


ABSTRACT: 1. The action of beryllium on the following enzymes has been examined: alkaline phosphatase (Escherichia coli and kidney), acid phosphatase, phosphoprotein phosphatase, apyrase (potato), adenosine triphosphatase (liver nuclei, liver mitochondria, brain microsomes), glucose 6-phosphatase, polysaccharide phosphorylases a and b, phosphoglucomutase, hexokinase, phosphoglyceromutase, ribonuclease, A-esterase (rabbit serum), cholinesterase (horse serum), chymotrypsin. Alkaline phosphatase and phosphoglucomutase are inhibited by 1mum-beryllium sulphate whereas the other enzymes are largely unaffected by 1mm-beryllium sulphate. 2. Possible mechanisms for the inhibition of phosphoglucomutase and alkaline phosphatase are discussed.

SUBMITTER: Thomas M 

PROVIDER: S-EPMC1264799 | BioStudies | 1966-01-01

SECONDARY ACCESSION(S): 10.1042/bj0980094

REPOSITORIES: biostudies

Similar Datasets

1966-01-01 | S-EPMC1264800 | BioStudies
1968-01-01 | S-EPMC1198584 | BioStudies
1970-01-01 | S-EPMC1179644 | BioStudies
1966-01-01 | S-EPMC1264852 | BioStudies
1000-01-01 | S-EPMC5224864 | BioStudies
2020-01-01 | S-EPMC7664937 | BioStudies
2018-01-01 | S-EPMC5955034 | BioStudies
2013-01-01 | S-EPMC3883670 | BioStudies
2016-01-01 | S-EPMC5096984 | BioStudies
2019-01-01 | S-EPMC6771974 | BioStudies