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Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines.


ABSTRACT: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection.HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types.A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.

SUBMITTER: Cuschieri K 

PROVIDER: S-EPMC2833249 | BioStudies | 2010-01-01

REPOSITORIES: biostudies

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