Unknown

Dataset Information

0

Stereoselective synthesis of morpholines via copper-promoted oxyamination of alkenes.


ABSTRACT: A new copper(II) 2-ethylhexanoate-promoted addition of an alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to excellent yields and diastereoselectivities.

SUBMITTER: Sequeira FC 

PROVIDER: S-EPMC3465956 | BioStudies | 2012-01-01

REPOSITORIES: biostudies

Similar Datasets

1000-01-01 | S-EPMC4734347 | BioStudies
2015-01-01 | S-EPMC4419545 | BioStudies
2009-01-01 | S-EPMC2709957 | BioStudies
2012-01-01 | S-EPMC3422551 | BioStudies
2019-01-01 | S-EPMC6980349 | BioStudies
2010-01-01 | S-EPMC2920148 | BioStudies
2012-01-01 | S-EPMC3369273 | BioStudies
2020-01-01 | S-EPMC7146911 | BioStudies
2019-01-01 | S-EPMC6803049 | BioStudies
2015-01-01 | S-EPMC4448762 | BioStudies