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SubNet: a Java application for subnetwork extraction.


ABSTRACT: The extraction of targeted subnetworks is a powerful way to identify functional modules and pathways within complex networks. Here, we present SubNet, a Java-based stand-alone program for extracting subnetworks, given a basal network and a set of selected nodes. Designed with a graphical user-friendly interface, SubNet combines four different extraction methods, which offer the possibility to interrogate a biological network according to the question investigated. Of note, we developed a method based on the highly successful Google PageRank algorithm to extract the subnetwork using the node centrality metric, to which possible node weights of the selected genes can be incorporated.http://www.zdzlab.org/1/subnet.html

SUBMITTER: Lemetre C 

PROVIDER: S-EPMC3777115 | BioStudies | 2013-01-01T00:00:00Z

REPOSITORIES: biostudies

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