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Effects of a high-intensity functional exercise program on depressive symptoms among people with dementia in residential care: a randomized controlled trial.

ABSTRACT: The aim of this study is to evaluate the effect of a high-intensity functional exercise program on depressive symptoms among older care facility residents with dementia.Residents (n?=?186) with a diagnosis of dementia, age???65?years, Mini-Mental State Examination score???10, and dependence in activities of daily living were included. Participants were randomized to a high-intensity functional exercise program or a non-exercise control activity conducted 45?min every other weekday for 4?months. The 15-item Geriatric Depression Scale (GDS) and the Montgomery-Åsberg Depression Rating Scale (MADRS) were administered by blinded assessors at baseline, 4, and 7?months.No difference between the exercise and control activity was found in GDS or MADRS score at 4 or 7?months. Among participants with GDS scores???5, reductions in GDS score were observed in the exercise and control groups at 4?months (-1.58, P?=?0.001 and -1.54, P?=?0.004) and 7?months (-1.25, P?=?0.01 and -1.45, P?=?0.007). Among participants with MADRS scores???7, a reduction in MADRS score was observed at 4?months in the control group (-2.80, P?=?0.009) and at 7?months in the exercise and control groups (-3.17, P?=?0.003 and -3.34, P?=?0.002).A 4-month high-intensity functional exercise program has no superior effect on depressive symptoms relative to a control activity among older people with dementia living in residential care facilities. Exercise and non-exercise group activities may reduce high levels of depressive symptoms.


PROVIDER: S-EPMC5215547 | BioStudies | 2016-01-01T00:00:00Z

REPOSITORIES: biostudies

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