Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels.
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ABSTRACT: A cisplatin templated nanogel with targeting capability was synthesized, inspired by cisplatin as a chemotherapeutic drug. After crosslinking the natural polysaccharide hyaluronan, a ligand for CD44, cisplatin could be removed by simple dialysis in a salt solution while the withheld drug remains entrapped.
SUBMITTER: Zhang W
PROVIDER: S-EPMC5319414 | BioStudies | 2017-01-01
REPOSITORIES: biostudies
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