Dataset Information


Is a positive Christie-Atkinson-Munch-Peterson (CAMP) test sensitive enough for the identification of Streptococcus agalactiae?

ABSTRACT: BACKGROUND:For a long time, the Christie-Atkinson-Munch-Peterson (CAMP) test has been a standard test for the identification of Streptococcus agalactiae, and a positive result for S.agalactiae has been considered sensitive enough. METHODS:To confirm whether a positive CAMP test is a requirement for the identification of S.agalactiae, five suspected CAMP-negative S.agalactiae isolates from two hospitals, confirmed as Gram-positive and catalase-negative streptococci, were verified by the CAMP test in three batches of plates from two manufacturers and identified by the Phoenix system, MALDI-TOF MS, the PCR assay and the 16S rDNA gene sequencing. RESULTS:All five suspected strains were S.agalactiae, four of which were CAMP-negative and one of which was not S.agalactiae by the PCR assay. CONCLUSIONS:A positive CAMP test was lacking sensitivity for the identification of S.agalactiae, and the question of whether the cfb gene is worthy of targeting should be further studied.


PROVIDER: S-EPMC6318942 | BioStudies | 2019-01-01


REPOSITORIES: biostudies

Similar Datasets

2011-01-01 | S-EPMC3388602 | BioStudies
2018-01-01 | S-EPMC5762925 | BioStudies
2005-01-01 | S-EPMC1168562 | BioStudies
2011-01-01 | S-EPMC3057116 | BioStudies
2011-01-01 | S-EPMC3075254 | BioStudies
1000-01-01 | S-EPMC3708387 | BioStudies
2010-01-01 | S-EPMC3224659 | BioStudies
2018-01-01 | S-EPMC6186353 | BioStudies
2017-01-01 | S-EPMC5543624 | BioStudies
2020-01-01 | S-EPMC7456362 | BioStudies