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NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterialresistance to anti-tuberculosis drugs

ABSTRACT: To identify the genes with napM-dependent differential expression, the gene expression profiles of the wild-type M. smegmatis strain and the napM-deleted strains were compared. For this case, the genes with fold changes exceeding 2 (P < 0.05) were considered significant. Strikingly, 156 genes were found to be differentially expressed in the absence of napM. Among these genes,121 were upregulated and 35 were downregulated.

ORGANISM(S): Mycolicibacterium smegmatis MC2 155

PROVIDER: GSE80817 | GEO | 2016/04/30

SECONDARY ACCESSION(S): PRJNA320080

REPOSITORIES: GEO

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