Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PAe004331PAe004320PAe004328PAe004336PAe000247PAe004338PAe004325PAe004323PAe004330PAe004329PAe004319PAe004337PAe004322PAe004327PAe004333PAe003810PAe004335PAe004334PAe004321PAe000240PAe004326PAe004324PAe004332
TISSUE(S): Prostate
SUBMITTER: Wangxin,Guo
REPOSITORIES: NODE
Nature genetics 20200817 9
The identification of prostate stem/progenitor cells and characterization of the prostate epithelial cell lineage hierarchy are critical for understanding prostate cancer initiation. Here, we characterized 35,129 cells from mouse prostates, and identified a unique luminal cell type (termed type C luminal cell (Luminal-C)) marked by Tacstd2, Ck4 and Psca expression. Luminal-C cells located at the distal prostate invagination tips (termed Dist-Luminal-C) exhibited greater capacity for organoid for ...[more]