Genomics

Dataset Information

0

Rattus norvegicus


ABSTRACT: Microarray analysis of rat mammary carcinogenesis

ORGANISM(S): Rattus norvegicus  

PROVIDER: PRJNA109839 | ENA |

REPOSITORIES: ENA

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Publications

Gene expression profiling during rat mammary carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.

Souda Masakazu M   Umekita Yoshihisa Y   Abeyama Kazuhiro K   Yoshida Hiroki H  

International journal of cancer 20090901 6


7,12-Dimethylbenz[a]anthracene (DMBA)-induced rat mammary carcinoma is a well-recognized model; however, the genetic alterations during its carcinogenesis have yet to be determined. We used laser capture microdissection to specifically isolate cells from terminal end buds (TEBs), the origin of carcinoma, at 2 weeks after sesame oil treatment (control) or DMBA treatment (DMBA-TEBs), ductal carcinoma in situ (DCIS) and invasive mammary carcinoma (MC). Using an oligonucleotide microarray representi  ...[more]

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