Genomics

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ABSTRACT: Transcriptomic analysis of milk somatic cells in mastitis resistant and susceptible sheep upon challenge with Staphylococcus epidermidis and Staphylococcus aureus

PROVIDER: PRJNA132179 | ENA |

REPOSITORIES: ENA

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Transcriptomic analysis of milk somatic cells in mastitis resistant and susceptible sheep upon challenge with Staphylococcus epidermidis and Staphylococcus aureus.

Bonnefont Cécile M D CM   Toufeer Mehdi M   Caubet Cécile C   Foulon Eliane E   Tasca Christian C   Aurel Marie-Rose MR   Bergonier Dominique D   Boullier Séverine S   Robert-Granié Christèle C   Foucras Gilles G   Rupp Rachel R  

BMC genomics 20110428


<h4>Background</h4>The existence of a genetic basis for host responses to bacterial intramammary infections has been widely documented, but the underlying mechanisms and the genes are still largely unknown. Previously, two divergent lines of sheep selected for high/low milk somatic cell scores have been shown to be respectively susceptible and resistant to intramammary infections by Staphylococcus spp. Transcriptional profiling with an 15K ovine-specific microarray of the milk somatic cells of s  ...[more]

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