Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) miRNA

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA186784 | ENA |

REPOSITORIES: ENA

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Publications

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS).

Jernås Margareta M   Malmeström Clas C   Axelsson Markus M   Nookaew Intawat I   Wadenvik Hans H   Lycke Jan J   Olsson Bob B  

BMC immunology 20130729


BACKGROUND: MicroRNA are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed genome-wide expression analyses of mRNA and microRNA in T-cells from MS patients and controls. METHODS: Heparin-anticoagulated peripheral blood was collected from MS-patients and healthy controls followed by isolation of T-cells. MicroRNA and RNA from T-cells was prepared and hybridized to Affymetrix miR 2.0 array  ...[more]

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