Dataset Information


Homo sapiens

ABSTRACT: MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) mRNA

ORGANISM(S): Homo sapiens  



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MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS).

Jernås Margareta M   Malmeström Clas C   Axelsson Markus M   Nookaew Intawat I   Wadenvik Hans H   Lycke Jan J   Olsson Bob B  

BMC immunology 20130729

BACKGROUND: MicroRNA are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed genome-wide expression analyses of mRNA and microRNA in T-cells from MS patients and controls. METHODS: Heparin-anticoagulated peripheral blood was collected from MS-patients and healthy controls followed by isolation of T-cells. MicroRNA and RNA from T-cells was prepared and hybridized to Affymetrix miR 2.0 array  ...[more]

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