Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Real-time quantitative PCR analysis of microRNA expression in neonatal and adult cardiovascular progenitors

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA213327 | ENA |

REPOSITORIES: ENA

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Publications

Human neonatal cardiovascular progenitors: unlocking the secret to regenerative ability.

Fuentes Tania I TI   Appleby Nancy N   Tsay Eric E   Martinez J Julian JJ   Bailey Leonard L   Hasaniya Nahidh N   Kearns-Jonker Mary M  

PloS one 20131028 10


Although clinical benefit can be achieved after cardiac transplantation of adult c-kit+ or cardiosphere-derived cells for myocardial repair, these stem cells lack the regenerative capacity unique to neonatal cardiovascular stem cells. Unraveling the molecular basis for this age-related discrepancy in function could potentially transform cardiovascular stem cell transplantation. In this report, clonal populations of human neonatal and adult cardiovascular progenitor cells were isolated and charac  ...[more]

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