Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: PBMC gene expression of early onset of the first demyelinating event of acute optic neuritis

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA264475 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

The role of B cells in the early onset of the first demyelinating event of acute optic neuritis.

Feldman Anna A   Gurevich Michael M   Huna-Baron Ruth R   Achiron Anat A  

Investigative ophthalmology & visual science 20150115 2


PURPOSE: We evaluated the molecular pathways that operate in the early phase of acute optic neuritis (ON) by studying gene expression profiles of peripheral blood mononuclear cells (PBMCs) subpopulations, including CD19(+) B cells, CD14(+) macrophages, and CD4(+) and CD8(+) T cells. METHODS: Samples of PBMC subpopulations were obtained from 18 MS patients within 96 hours of the acute onset of the first demyelinating event of ON, and from 14 age- and sex-matched healthy subjects. High throughput  ...[more]

Similar Datasets

2014-10-22 | E-GEOD-62584 | ArrayExpress
| GSE62584 | GEO
2011-02-14 | GSE20307 | GEO
2011-02-14 | E-GEOD-20307 | ArrayExpress
| PRJNA97185 | ENA
| PRJNA326858 | ENA
2013-01-26 | E-GEOD-43777 | ArrayExpress
2014-04-23 | E-MEXP-3917 | ArrayExpress
2008-10-25 | E-GEOD-11862 | ArrayExpress
2008-09-01 | GSE11862 | GEO