Genomics

Dataset Information

294


ABSTRACT: Next Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes

PROVIDER: PRJNA266762 | ENA |

REPOSITORIES: ENA

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Publications


Spermatogenesis consists broadly of three phases: proliferation of diploid germ cells, meiosis, and finally extensive differentiation of the haploid cells into effective delivery vehicles for the paternal genome. Despite detailed characterization of many haploid developmental steps leading to sperm, only fragmentary information exists on the control of gene expression underlying these processes. Here we report that the RFX2 transcription factor is a master regulator of genes required for the hap  ...[more]

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