Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Transcriptome analysis in medulloblastoma groups

PROVIDER: PRJNA281073 | ENA |

REPOSITORIES: ENA

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Publications

Integrated genomics has identified a new AT/RT-like yet INI1-positive brain tumor subtype among primary pediatric embryonal tumors.

Ho Donald Ming-Tak DM   Shih Chuan-Chi CC   Liang Muh-Lii ML   Tsai Chan-Yen CY   Hsieh Tsung-Han TH   Tsai Chin-Han CH   Lin Shih-Chieh SC   Chang Ting-Yu TY   Chao Meng-En ME   Wang Hsei-Wei HW   Wong Tai-Tong TT  

BMC medical genomics 20150625


<h4>Background</h4>Pediatric embryonal brain tumors (PEBTs), which encompass medulloblastoma (MB), primitive neuroectodermal tumor (PNET) and atypical teratoid/rhabdoid tumor (AT/RT), are the second most prevalent pediatric brain tumor type. AT/RT is highly malignant and is often misdiagnosed as MB or PNET. The distinction of AT/RT from PNET/MB is of clinical significance because the survival rate of patients with AT/RT is substantially lower. The diagnosis of AT/RT relies primarily on morpholog  ...[more]

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