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Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants

ABSTRACT: Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants

PROVIDER: PRJNA357453 | ENA |

REPOSITORIES: ENA

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Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants [Nanostring]

Project description:Aging is a time-dependent biological phenomenon governed by complex networks of regulatory components and their transitions over lifetime. Yet, there have been limited efforts to pin down age-associated networks and map their dynamic characteristics onto aging phenotypes. Here, we built time-course genetic regulatory networks of NAM/ATAF/CUC (NAC) transcription factors during the course of leaf aging in Arabidopsis, using causal regulatory relationships among NACs identified from mutants of 49 aging-associated NACs. These temporal networks revealed a regulatory inversion from activating to repressive regulatory modes at a pre-senescent stage. The inversion was governed by three hub NACs, and their mutants conferred earlier aging with altered expression of reactive oxygen species and salicylic acid response genes. Overexpression of the hub NACs delayed the regulatory inversion, rendering delayed age-dependent cell death. We conclude that the regulatory inversion in NAC networks at a pre-senescent stage directs when age-dependent cell death should proceed in plants.

2018-04-29 | GSE92369 | GEO

Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants [RNA-Seq]

2018-04-29 | GSE92314 | GEO

E-GEOD-92314

Project description:Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants [RNA-Seq]

2020-04-15 | E-GEOD-92314 | ExpressionAtlas

Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-04-29 | GSE92371 | GEO

Arabidopsis thaliana

Project description:Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants [Nanostring]

| PRJNA357454 | ENA

Arabidopsis thaliana

Project description:Regulatory inversion in NAC networks steers the timing of age-dependent cell death in plants [RNA-Seq]

| PRJNA357201 | ENA

Muscle in beef steers with low vs. high residual feed efficiency

Project description:Transcriptional profiling of bovine skeletal muscle comparing metabolically efficient steers to metabolically inefficient steers to ascertain what expression differences can be found in muscle tissue that might help explain differences in this economically significant phenotype. Two condition experiment, efficient versus inefficient animals. 8 efficient and 8 inefficient samples were used representing 16 unique individual animals.

2014-04-11 | E-GEOD-56705 | biostudies-arrayexpress

Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC

Project description:In this study, NAC was UV-crosslinked using the photo-crosslinking amino acid p-benzoyl-L-phenylalanine (pBPA) in order to determine specific interaction sites of the alphaNAC N-terminus in the native protein structure. Furthermore, quantitative chemical crosslinking coupled to mass spectrometry (q-XL-MS) was used to compare crosslink abundances of a NAC mutant versus wild type NAC in order to determine the influence of the mutated motive on the structural dynamics of NAC.

2019-07-25 | PXD011995 | Pride

Muscle in beef steers with low vs. high residual feed efficiency

2014-04-11 | GSE56705 | GEO

Hepatic Gene Expression Profiles of Growing versus Finished Beef Steers

Project description:Growing and finishing phases are two important animal production stages, which differ fundamentally in compositional growth. However, the physiological mechanisms altered concomitantly with the shift in whole-body compositional gain as cattle fatten (growing vs. finished steers), are poorly understood. Microarray analysis using the Bovine Gene 1.0 ST Array was conducted to determine shifts in hepatic genomic expression profiles of growing vs. finishing beef steers. The specific overall hypothesis tested was that genes involved in amino acid, carbohydrate and lipid metabolism, antioxidant capacity and immune responses were differentially expressed in growing vs. finishing steers.

2017-12-11 | GSE107881 | GEO

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