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Excretory/secretory microRNAs from the gastrointestinal nematode Trichuris muris in culture

ABSTRACT: Excretory/secretory microRNAs from the gastrointestinal nematode Trichuris muris in culture

OTHER RELATED OMICS DATASETS IN: GSE93667GSE93733

PROVIDER: PRJNA361495 | ENA |

REPOSITORIES: ENA

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Excretory/secretory microRNAs from the gastrointestinal nematode Trichuris muris in culture

Project description:We report analyses of the types and amounts of microRNAs found in culture media recovered after incubating approximately 3000 T. muris adult worms for 48 hours.

2017-09-01 | GSE93667 | GEO

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Trichuris muris transcriptomics

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Extracellular vesicles Trichuris muris

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mRNA data from extracellular vesicles secreted by Trichuris muris

Project description:RNA-Seq analysis of the mRNA present in the extracellular vesicles secreted by the nematode Trichuris muris

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miRNA data from extracellular vesicles secreted by Trichuris muris

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Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct small RNAs

Project description:We report the small RNA content of extracellular vesicles (EVs) from adult parasite Trichuris muris and Heligmosomoides bakeri

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Transcriptional response of the mouse intestinal mucosa to infection by the parasitic nematode Trichuris muris

Project description:This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ The human-infective whipworm Trichuris trichiura is estimated to infect up to a billion people and is responsible for considerable morbidity, especially in children of developing countries. The closely related species T. muris is a naturally occurring nematode parasite of mice that serves as a remarkably tractable model system for dissecting immune responses and host-parasite relationships. Such studies are of relevance beyond parasitology as helminths have arguably had a significant impact on the evolution of the mammalian immune system. Both Trichuris species reside in the caecum and colon of the host where they burrow their front end for feeding into the intestinal mucosa, thereby breaching the mucus barrier and allowing access of the microflora directly to the epithelium. The interplay of intestinal helminths, the bacterial microflora and the host immune system is currently a research focus in various laboratories (Bancroft et al 2012). This study will study the transcriptional responses of the intestinal mucosa (caecum) from infected and uninfected mice.

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Excretory/secretory microRNAs from the gastrointestinal nematode Heligmosomoides polygyrus bakeri in culture.

Project description:Excretory/secretory microRNAs from the gastrointestinal nematode Heligmosomoides polygyrus bakeri in culture.

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