Genomics

Dataset Information

0

Brassica napus


ABSTRACT: Brassica napus

ORGANISM(S): Brassica napus  

PROVIDER: PRJNA371363 | ENA |

REPOSITORIES: ENA

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Publications

Studies of lipoxygenase function.

McCabe NP  

20110323


Arachidonic acid metabolism leads to the production of biolipid mediatiors with important roles in multiple pathological processes including prostate cancer. Expression of platelet-type 12-lipoxygenase (P12-LOX) correlates with clinical stage and grade of prostate adenocarcinoma and overexpression in prostate cancer cells leads to large, highly vascularized tumors in a mouse model. The product of arachidonic acid metabolism via P12-LOX is 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE), a lipid  ...[more]

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