Dataset Information


ABSTRACT: Comprehensive analysis of OXA-48 producing Escherichia coli from a Spanish hospital using whole genome sequencing combined with conventional typing tools



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Whole genome sequencing, molecular typing and in vivo virulence of OXA-48-producing Escherichia coli isolates including ST131 H30-Rx, H22 and H41 subclones.

de Toro María M   Fernández Javier J   García Vanesa V   Mora Azucena A   Blanco Jorge J   de la Cruz Fernando F   Rodicio M Rosario MR  

Scientific reports 20170921 1

Carbapenem-resistant Enterobacteriaceae, including the increasingly reported OXA-48 Escherichia coli producers, are an emerging public health threat worldwide. Due to their alarming detection in our healthcare setting and their possible presence in the community, seven OXA-48-producing, extraintestinal pathogenic E. coli were analysed by whole genome sequencing as well as conventional tools, and tested for in vivo virulence. As a result, five E. coli OXA-48-producing subclones were detected (O25  ...[more]

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