Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole genome sequencing of Burkholderia cepacia from an outbreak associated with contaminated octenidine mouthwash solution

ABSTRACT: Whole genome sequencing of Burkholderia cepacia from an outbreak associated with contaminated octenidine mouthwash solution

PROVIDER: PRJEB28814 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2814670_1.fastq.gz	Fastqsanger.gz
	ERR2814670_2.fastq.gz	Fastqsanger.gz
	ERR2814671_1.fastq.gz	Fastqsanger.gz
	ERR2814671_2.fastq.gz	Fastqsanger.gz
	ERR2814672_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Burkholderia cepacia complex outbreak originating from contaminated washing gloves, Switzerland, June 2019

Project description:Burkholderia cepacia complex outbreak originating from contaminated washing gloves, Switzerland, 2019

| PRJEB34276 | ENA

Burkholderia cepacia

Project description:Novel Burkholderia cepacia outbreak in the US

| PRJNA297031 | ENA

Outbreak of <i>Burkholderia cepacia</i> complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018.

Project description:Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.

| S-EPMC6199865 | biostudies-literature

<i>Burkholderia cepacia</i> complex outbreak originating from contaminated wash gloves.

Project description:Burkholderia cepacia complex isolates were detected from four patients who were admitted to the heart centre of southern Switzerland, between April and June 2019. An outbreak investigation was conducted. The three available patient samples were whole genome sequenced, showing that they all are Burkholderia cepacia species, and that two are identical. Isolates grown from sealed packages of disinfectant-free wash gloves used for personal hygiene were also genomically identical. The wash gloves appear to be the origin of the outbreak, contamination of which most likely occurred at the manufacturing site.

| S-EPMC8335913 | biostudies-literature

Expression data from Burkholderia cepacia IST408 bceE and bceF mutants

Project description:The bacterial tyrosine (BY) kinase family comprises the major group of bacterial enzymes endowed with tyrosine kinase activity. We have previously shown that the BceF protein from Burkholderia cepacia IST408 belongs to this BY kinase family and is involved in the biosynthesis of the exopolysaccharide cepacian. However, little is known about the extent of regulation in the cell by this kinase protein. In order to examine this, we performed a comparative transcriptome profile between the bceF mutant and the wild-type B. cepacia IST408. As a control, the transcriptome of another exopolysaccharide-deficient mutant, which had a mutation in the bceE gene, was also determined.

2012-12-01 | GSE38183 | GEO

Project description:To determine if differences in the severity of pulmonary infection in cystic fibrosis been seen in late isolates od Pseudomonas aeruginosa and Burkholderia cepacia are associated with differences in the initial repsonse of alveolar macrophages (AM) to these pathogens, we assessed gene expression changes in human AM in response to infection with a laboratoty strain, early and late clinical isolates of P. aeruginosa, and B. cepacia. Keywords: Comparison of gene expression in alveolar macrophages of normal non-smokers and normal smokers.

2008-07-26 | GSE12245 | GEO

Bacteria solution

Project description:Bacteria solution Raw sequence reads

| PRJNA1278922 | ENA

Polyclonal Burkholderia cepacia Complex Outbreak in Peritoneal Dialysis Patients Caused by Contaminated Aqueous Chlorhexidine.

Project description:Whether Burkholderia cepacia complex should be an objectionable organism in antiseptic solutions with acceptable total bacterial counts is controversial. By using next-generation sequencing, we documented a polyclonal B. cepacia complex outbreak affecting peritoneal dialysis patients in Hong Kong that was caused by contaminated chlorhexidine solutions. Epidemiologic investigations at a manufacturing site identified a semiautomated packaging machine as the probable source of contamination in some of the brands. Use of whole-genome sequencing differentiated the isolates into 3 brand-specific clonal types. Changes in exit site care recommendations, rapid recall of affected products, and tightening of regulatory control for chlorhexidine-containing skin antiseptics could prevent future similar outbreaks. Environmental opportunistic pathogens, including B. cepacia complex, might be included in regular surveillance as indicator organisms for monitoring environmental contamination.

| S-EPMC7454066 | biostudies-literature

Burkholderia cepacia

Project description:Burkholderia cepacia Genome sequencing

| PRJNA863394 | ENA

Burkholderia cepacia

Project description:Burkholderia cepacia Genome sequencing

| PRJNA1183809 | ENA