{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":[null],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BIAD1091"],"repository":["bioimages"],"figure_sub":["Specimen","Image analysis","Study Component","organisation","Biosample","Associations","Image acquisition"],"pubmed_authors":["Mafalda Almeida","Neil Brockdorff","Joseph Bowness"],"additional_accession":[]},"is_claimable":false,"name":"RNA-FISH of Xist in iXist-ChrX mouse embryonic stem cells upon acute degradation of YY1","description":"Here we provide the raw RNA-FISH images displayed in the study \"YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing\". These images were collected from iXist-ChrX mouse embryonic stem cell lines engineered with the FKBP12 degron tag fused to endogenous YY1, such that addition of dTAG-13 acutely degrades YY1 protein from cells. Degradation of YY1 - either prior to Xist induction or after prolonged Xist induction - has little effect on the appearance of Xist RNA territories over the Xi chromosome. ","dates":{"release":"2024-03-23T00:00:00Z","modification":"2024-03-24T12:38:56.57Z","creation":"2024-03-23T18:12:40.607Z"},"accession":"S-BIAD1091","cross_references":{}}