{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":[null],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BIAD1119"],"repository":["bioimages"],"figure_sub":["Specimen","Study Component","organisation","Biosample","Associations","Image acquisition"],"pubmed_authors":["Anne Rios"],"additional_accession":[]},"is_claimable":false,"name":"Source Images A multispectral 3D live organoid imaging platform to screen probes for fluorescence guided surgery","description":"Achieving complete tumor resection is challenging and can be improved by real-time fluorescence guided surgery with molecular-targeted probes. However, pre-clinical identification and validation of probes presents a lengthy process that is traditionally performed in animal models and hampered by inter- and intra-tumoral heterogeneity in target expression. To screen multiple probes at patient scale, we developed a multispectral real-time 3D imaging platform that implements organoid technology to effectively model patient tumor heterogeneity and, importantly, healthy human tissue binding. ","dates":{"release":"2024-04-25T00:00:00Z","modification":"2024-04-26T08:49:15.838Z","creation":"2024-04-15T15:02:01.571Z"},"accession":"S-BIAD1119","cross_references":{}}