{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":[null],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BIAD1483"],"repository":["bioimages"],"figure_sub":["Specimen","Funding","Study Component","organisation","Biosample","Associations","Image acquisition"],"pubmed_authors":["alain burette"],"additional_accession":[]},"is_claimable":false,"name":"Regional expression of myelin basic protein across postnatal brain development of C57BL/6J mice","description":"Healthy brain development hinges on proper myelination. Disruptions in this process result in a variety of neurological disorders. Myelin basic protein (MBP) immunohistochemistry is a key method for studying myelination and myelin-related disorders. Despite MBP studies dating back to the 1980s, there has been a surprising lack of detailed accounts of normal MBP progression across the developing mouse brain. This study presents a detailed spatiotemporal view of MBP distribution across 12 developmental ages from postnatal day 2 to 60. We used an optimized immunohistochemistry protocol to overcome the challenges of myelin's unique lipid-rich composition, enabling more consistent staining across diverse brain structures and developmental stages. ","dates":{"release":"2024-11-26T00:00:00Z","modification":"2025-02-07T11:12:15.865Z","creation":"2024-11-19T14:56:11.697Z"},"accession":"S-BIAD1483","cross_references":{}}