{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":[null],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-BIAD658"],"repository":["bioimages"],"figure_sub":["Specimen","Image analysis","Study Component","organisation","Biosample","Associations","Image acquisition"],"pubmed_authors":["Michael Chang","Tulio Valdez","Thomas Bischof","Oliver Bruns","Stella Yang","Tjadina Klein","Jayakar Nayak","Mahbuba Afrin Tusty"],"additional_accession":[]},"is_claimable":false,"name":"Development of a shortwave infrared (SWIR) sinuscope for the detection of cerebrospinal fluid (CSF) leaks.","description":"Significance: CSF rhinorrhea (leakage of brain fluid from the nose) can be difficult to identify and currently requires invasive procedures such as intrathecal fluorescein which requires a lumbar drain placement. Fluorescein is also known to have rare but significant side effects including seizures and death. As the number of endonasal skull base cases increase, the number of CSF leaks have also increased for which an alternative diagnostic method would be highly advantageous to patients.\nAim:  To develop an instrument to identify CSF leaks based on water absorption in the SWIR without the need of intrathecal contrast agents. This device needed to be adapted to the anatomy of the human nasal cavity while maintaining low weight and ergonomic characteristics of current surgical instruments.\n","dates":{"release":"2023-03-21T00:00:00Z","modification":"2023-03-27T12:17:21.332Z","creation":"2023-03-27T12:17:21.332Z"},"accession":"S-BIAD658","cross_references":{}}