{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Gul Civelekoglu-Scholey"],"journal":["The Journal of Cell Biology"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-JCBD-200908150"],"attach_to":["JCB"],"legend":["The microinjection of a mixture of anti-lamin-B mAbs crosslinks the lamin-B envelope into a hyperstable network that fails to disassemble and remains throughout mitosis. This<br />structure impedes spindle elongation.","Embryo expressing lamin-B-GFP injected with rhodamine tubulin.  This embryo was imaged under the same conditions as that injected with antibody.","3D stack of an embryo expressing KLP61F-GFP during prometaphase phase 1","Cycle 11 timelapse of an embryo expressing gfp-tubulin (shown in red) and histone-rfp (shown in green)","Microinjection of the lamin-B tail dominant negative subfragment disrupts the nuclear lamina and causes defects in mitosis","Time lapse of an embryo expressing lamin-B-GFP injected with rhodamine tubulin.","Cycle 11 timelapse of an embryo expressing gfp-tubulin (shown in green) and histone-rfp (shown in red).  4 planes (0.5 microns) were acquired","3D stack of an embryo expressing Ncd-GFP during prometaphase phase 1"],"repository":["bioimages"],"figure_sub":["Figure 5 - A","Image 7995 (Figure 1 - B)","Image 7990 (Figure 5 - A)","Image 8072 (Figure 6 - B)","Figure 1 - A","Image 8071 (Figure 1 - A)","Figure 1 - B","Figure 5","SupFigure 1","Figure 6","Image 7994 (Figure 1 - B)","Image 8085 (Figure 6 - A)","SupFigure 1 - None","Image 8033 (SupFigure 1 - None)","Figure 6 - A","Figure 6 - B","Figure 1","Image 8032 (Figure 6 - B)"],"pubmed_authors":["Jonathan M. Scholey","Li Tao","Ingrid Brust-Mascher","Gul Civelekoglu-Scholey","Roy Wollman"],"additional_accession":[]},"is_claimable":false,"name":"Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope","description":null,"dates":{"release":"2010-01-11T11:18:29Z","modification":"2018-11-29T11:18:29Z","creation":"2018-11-29T11:18:29Z"},"accession":"S-JCBD-200908150","cross_references":{"doi":["10.1083/jcb.200908150"]}}