{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Arundhati Sengupta Ghosh"],"journal":["The Journal of Cell Biology"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-JCBD-201103153"],"attach_to":["JCB"],"legend":["Tuj1 staining in DLK (-/-) DRG explants. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in WT and cJun (lox/lox) neurons, but no activation is observed in DLK-/- neurons.","Immunohistochemical staining of lumbar level DRG from E17.5 DLK (-/-) littermates with a Pan-Trk antibody. DLK (-/-) DRGs (B) appear larger and contain more Trk positive neurons than WT controls (A).","Activated Caspase 9 staining in DLK (-/-) DRG explants. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in WT and cJun (lox/lox) neurons, but no activation is observed in DLK (-/-) neurons.","Activated Caspase 9 staining in cJun (lox/lox) DRG explants. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in WT and cJun (lox/lox) neurons.","Tuj1 staining in cJUN (lox/lox) DRG explants. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in WT and cJun (lox/lox) neurons.","Immunohistochemical staining of lumbar level DRG from E17.5 WT (DLK+/+) littermates with a Pan-Trk antibody. DLK (-/-) DLK (-/-) DRGs (B) appear larger and contain more Trk positive neurons than WT controls (A).","Activated Caspase 9 staining in DRG explants from cJun WT  DRG explants. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in c Jun WT neurons.","Tuj1 staining in DRG explants from cJun WT. Caspase 9 is activated in many axons after 8 hours of NGF withdrawal in cJun WT neurons."],"repository":["bioimages"],"figure_sub":["Fig 6 - O","Image 32183 (Fig 6 - O)","Fig 6 - M","Fig 6 - N","Image 32176 (Fig 6 - M)","Fig 7 - A","Fig 7 - B","Fig 7","Fig 6","Image 32179 (Fig 6 - N)","Image 32180 (Fig 6 - O)","Image 32177 (Fig 6 - M)","Image 32182 (Fig 7 - B)","Image 32181 (Fig 7 - A)","Image 32178 (Fig 6 - N)"],"pubmed_authors":["Ryan J. Watts","Christine D. Pozniak","Bei Wang","Mark Chen","Arundhati Sengupta Ghosh","Joseph W. Lewcock"],"additional_accession":[]},"is_claimable":false,"name":"DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity","description":null,"dates":{"release":"2011-09-05T11:22:03Z","modification":"2018-11-29T11:22:03Z","creation":"2018-11-29T11:22:03Z"},"accession":"S-JCBD-201103153","cross_references":{"doi":["10.1083/jcb.201103153"]}}