{"database":"bioimages","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Sebastian Treusch"],"journal":["The Journal of Cell Biology"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-JCBD-201108146"],"attach_to":["JCB"],"legend":["Electron microscopy of a cryofixed [RNQ+] Rnq1-overexpressing yeast cell containing unduplicated spindle pole bodies (SPBs). The unduplicated SPBs in arrested [RNQ+] cells exhibited a range of abnormal morphologies. The SPBs lacked solid central plaques and often had reduced outer plaques (phenotypes 1 and 2). Some arrested SPBs presented with long half-bridges (phenotype 3) or had a bilobed morphology (phenotype 4 (shown here)).","Electron microscopy of a cryofixed [rnq-] Rnq1-overexpressing yeast cell containing normal elongated spindles.","Electron microscopy of a cryofixed [RNQ+] Rnq1-overexpressing yeast cell containing unduplicated spindle pole bodies (SPBs). The unduplicated SPBs in arrested [RNQ+] cells exhibited a range of abnormal morphologies. The SPBs lacked solid central plaques and often had reduced outer plaques (phenotypes 1 and 2 (shown here)). Some arrested SPBs presented with long half-bridges (phenotype 3) or had a bilobed morphology (phenotype 4).","Electron microscopy of a cryofixed [RNQ+] Rnq1-overexpressing yeast cell showing that [RNQ+] cells arrest with an unduplicated spindle pole body.","Electron microscopy of a cryofixed [RNQ+] Rnq1-overexpressing yeast cell containing unduplicated spindle pole bodies (SPBs). The unduplicated SPBs in arrested [RNQ+] cells exhibited a range of abnormal morphologies. The SPBs lacked solid central plaques and often had reduced outer plaques (phenotypes 1 (shown here) and 2). Some arrested SPBs presented with long half-bridges (phenotype 3) or had a bilobed morphology (phenotype 4).","Electron microscopy of a cryofixed [RNQ+] Rnq1-overexpressing yeast cell containing unduplicated spindle pole bodies (SPBs). The unduplicated SPBs in arrested [RNQ+] cells exhibited a range of abnormal morphologies. The SPBs lacked solid central plaques and often had reduced outer plaques (phenotypes 1 and 2). Some arrested SPBs presented with long half-bridges (phenotype 3 (shown here)) or had a bilobed morphology (phenotype 4)."],"repository":["bioimages"],"figure_sub":["Image 134273 (Figure 3 - C)","Image 134259 (Figure 3 - B)","Image 134265 (Figure 3 - C)","Image 134269 (Figure 3 - C)","Figure 3 - B","Figure 3 - C","Image 134280 (Figure 3 - B)","Image 134266 (Figure 3 - C)","Image 134274 (Figure 3 - C)","Image 134261 (Figure 3 - C)","Image 134270 (Figure 3 - C)","Image 134267 (Figure 3 - C)","Image 134260 (Figure 3 - B)","Image 134278 (Figure 3 - B)","Image 134262 (Figure 3 - C)","Image 134275 (Figure 3 - C)","Image 134271 (Figure 3 - C)","Image 134279 (Figure 3 - B)","Image 134277 (Figure 3 - C)","Image 134264 (Figure 3 - C)","Image 134263 (Figure 3 - C)","Image 134276 (Figure 3 - C)","Image 134268 (Figure 3 - C)","Image 134272 (Figure 3 - C)","Figure 3"],"pubmed_authors":["Sebastian Treusch","Susan Lindquist"],"additional_accession":[]},"is_claimable":false,"name":"An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component","description":null,"dates":{"release":"2012-04-23T11:22:26Z","modification":"2018-11-29T11:22:26Z","creation":"2018-11-29T11:22:26Z"},"accession":"S-JCBD-201108146","cross_references":{"doi":["10.1083/jcb.201108146"]}}