bioimagesUnknownBryan LoThe Journal of Cell Biologyhttps://www.ebi.ac.uk/biostudies/studies/S-JCBD-201208080JCB

Shown is a z-stack of a mouse E16.5 Lkb1 WT/MG pancreatic explant cultured on transwell filters for 8 days in vitro with 1μM 1NMPP1 and labeled for EpCAM (green), actin (red), and DNA (blue).

Shown is a mouse Lkb1 MG/MG E16.5 pancreatic explant cultured on transwell filters for 3 days in vitro with 1μM 1NMPP1 and labeled for actin (green), Muc-1 (purple), E-cadherin (red), and ZO-1 (white).

Shown is a developing cyst in a mouse Lkb1 WT/WT E16.5 pancreatic explant cultured on transwell filters for 3 days in vitro with 1μM 1NMPP1 and labeled for E-cadherin (green) and ZO-1 (white; shown as a projection across a 10μM z-stack).

Shown is a z-stack of a mouse Lkb1 WT/WT E12.5 pancreatic explant cultured on transwell filters for 3 days in vitro with 1μM 1NMPP1 and labeled for Muc-1 (green), E-cadherin (red), and ZO-1 (white).

Shown is a mouse E14.5 Kras WT/WT p16p19 -/- pancreatic explant cultured for 8 days in vitro and labeled for Muc-1 (green), E-cadherin (red), and ZO-1 (cyan). Note: Muc-1 and ZO-1 are shown as maximum projections across a 10μM z-stack; E-cadherin is a single section from the middle of the z-stack.

Shown is a mouse E14.5 Kras G12D/WT p16p19 -/- pancreatic explant cultured for 8 days in vitro and labeled for Muc-1 (green), E-cadherin (red), and ZO-1 (cyan). Note: Muc-1 and ZO-1 are shown as maximum projections across a 10μM z-stack; E-cadherin is a single section from the middle of the z-stack.

Shown is a z-stack of a mouse Lkb1 MG/MGWT E12.5 pancreatic explant cultured on transwell filters for 3 days in vitro with 1μM 1NMPP1 and labeled for Muc-1 (green), E-cadherin (red), and ZO-1 (white).

Shown is a mouse Lkb1 WT/WT E16.5 pancreatic explant cultured on transwell filters for 3 days in vitro with 1μM 1NMPP1 and labeled for actin (green), Muc-1 (purple), E-cadherin (red), and ZO-1 (white).

Shown is a z-stack of a mouse E16.5 Lkb1 MG/MG pancreatic explant cultured on transwell filters for 8 days in vitro with 1μM 1NMPP1 and labeled for EpCAM (green), actin (red), and DNA (blue).

Shown is a z-stack of a mouse E16.5 Lkb1 WT/MG pancreatic explant cultured on transwell filters for 8 days in vitro with 1μM 1NMPP1 and labeled for EpCAM (green), actin (red), and DNA (blue).<br />

bioimagesFigure 3 - DFigure 3 - EImage 139428 (Figure 7 - C)Image 139421 (Figure 3 - D)Image 139424 (Figure 6 - A)Image 139426 (Figure 6 - B)Figure 7 - CFigure 3 - BImage 139419 (Figure 3 - B)Figure 7Image 139420 (Figure 3 - D)Figure 6Image 139429 (Figure 7 - C)Image 139423 (Figure 3 - E)Image 139425 (Figure 6 - A)Image 139427 (Figure 6 - B)Image 139422 (Figure 3 - E)Figure 6 - AFigure 6 - BImage 139418 (Figure 3 - B)Figure 3Meredith SagollaCary D. AustinGeraldine StrasserIra MellmanMelissa JunttilaBryan LofalseLkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways2012-12-24T11:23:50Z2018-11-29T11:23:50Z2018-11-29T11:23:50ZS-JCBD-20120808010.1083/jcb.201208080