{"database":"BioModels","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Pdf":["https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000.pdf"],"Svg":["https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000.svg"],"Xml":["https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000_url.xml","https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000_urn.xml"],"Other":["https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000.vcml","https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000.sci","https://www.ebi.ac.uk/biomodels/model/download/MODEL1503050000?filename=MODEL1503050000.png"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"submitter":["Kieran Smallbone"],"curationStatus":["Non-curated"],"modellingApproach":["ordinary differential equation model"],"levelVersion":["L2V4"],"full_dataset_link":["https://www.ebi.ac.uk/biomodels/MODEL1503050000"],"isPrivate":["false"],"repository":["BioModels"],"non_derived_xrefs":["BIOMD0000000051 biomodels.db MODEL1501300000 biomodels.db"],"modelFormat":["SBML"],"omics_type":["Models"],"tokenised_name":["Smallbone2015   Multi scale model of E. coli metabolism"],"submissionId":["MODEL1503050000"],"publication_authors":["Smallbone K.1, Millard P.2"],"first_author":["Smallbone K.1"],"publication":["10.7287/peerj.preprints.914v1,\n                            In response to environmental and genetic perturbations, micro-organisms may regulate their metabolism both metabolically – via metabolite-enzyme interactions – and hierarchically – via modulating enzyme capacities. In this report, we develop a combined metabolic and genetic regulatory model of E. coli that may be used to test this multi-scale response.. null, null.\n                            1 Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, United Kingdom 2 INSA, UPS, INP, LISBP, INRA, UMR792 Ingenierie des Systemes Biologiques et des Procedes, CNRS, UMR550, Université de Toulouse, Toulouse, France"],"submitter_mail":["kieran.smallbone@ncl.ac.uk"],"publication_doi":["10.7287/peerj.preprints.914v1"],"submitter_affiliation":["Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK."],"additional_accession":[]},"is_claimable":false,"name":"Smallbone2015 - Multi-scale model of E. coli metabolism","description":"No description","dates":{"last_modification":"2016-02-10","publication":"2016-02-10","submission":"2015-03-05"},"accession":"MODEL1503050000","cross_references":{"kegg__reaction":["R00658","R01518","R00756","R00771","R01512","R00200","R01015","R00959","R00835","R02035","R01827","R01641","R01067","R01070","R01061","R00345","R00209","R01528","R01056","R01529","R00948"],"ec-code":["4.2.1.11","4.1.2.13","5.4.2.1","2.7.1.11","5.3.1.9","2.7.2.3","5.4.2.2","2.7.1.40","5.3.1.1","3.1.1.31","1.1.1.49","2.2.1.2","2.2.1.1","1.2.1.12","4.1.1.31","1.2.1.51","1.1.1.44","5.3.1.6","5.1.3.1","2.7.7.27"],"kegg__pathway":["rn00620"],"reactome":["REACT_1255","REACT_605","REACT_736","REACT_1272","REACT_162","REACT_1811","REACT_1602","REACT_1847","REACT_469","REACT_1186","REACT_576","REACT_1400","REACT_1524","REACT_611","REACT_6907","REACT_1522"],"chebi":["CHEBI:16108","CHEBI:17665","CHEBI:18021","CHEBI:15361","CHEBI:16077","CHEBI:4167","CHEBI:17234","CHEBI:15946","CHEBI:16863","CHEBI:16905","CHEBI:15721","CHEBI:17138","CHEBI:48153","CHEBI:16332","CHEBI:17797","CHEBI:16001","CHEBI:17794","CHEBI:17835","CHEBI:17363"],"biomodels__db":["MODEL1503050000"],"go":["GO:0004347","GO:0005576","GO:0005829"],"kegg__compound":["C00279","C00111","C05345","C00668","C00074","C00022","C00031","C00085","C00103","C00345","C00354","C00281","C00661","C00231","C00117","C00236","C00197","C00631","C00199"],"doi":["10.7287/peerj.preprints.914v1"]}}