{"database":"BioModels","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Xlsx":["https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=miniFROG%20Report_Cunha2022_leaf.xlsx"],"Xml":["https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=QuercusSuberLeaf.xml","https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=QuercusSuberLeaf_ht.xml","https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=QuercusSuberLeaf_pa.xml"],"Other":["https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=FROG_report_Leaf.zip","https://www.ebi.ac.uk/biomodels/model/download/MODEL2205040001?filename=Qsuber_leaf.html"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"submitter":["Emanuel Cunha"],"curationStatus":["Non-curated"],"modellingApproach":["constraint-based model"],"levelVersion":["L3V1"],"submitter_keywords":["FROG","Not Peer Reviewed"],"full_dataset_link":["https://www.ebi.ac.uk/biomodels/MODEL2205040001"],"isPrivate":["false"],"repository":["BioModels"],"modelFormat":["SBML"],"omics_type":["Models"],"tokenised_name":["Cunha2022   Leaf GSM model of Quercus suber"],"publication_year":["2023"],"submissionId":["MODEL2205040001"],"first_author":["Emanuel Cunha"],"publication_authors":["Emanuel Cunha, Miguel Silva, Inês Chaves, Huseyin Demirci, Davide Rafael Lagoa, Diogo Lima, Miguel Rocha, Isabel Rocha, Oscar Dias"],"publication":["10.1371/journal.pcbi.1011499,\n                            Over the last decade, genome-scale metabolic models have been increasingly used to study plant metabolic behaviour at the tissue and multi-tissue level under different environmental conditions. Quercus suber, also known as the cork oak tree, is one of the most important forest communities of the Mediterranean/Iberian region. In this work, we present the genome-scale metabolic model of the Q. suber (iEC7871). The metabolic model comprises 7871 genes, 6231 reactions, and 6481 metabolites across eight compartments. Transcriptomics data was integrated into the model to obtain tissue-specific models for the leaf, inner bark, and phellogen, with specific biomass compositions. The tissue-specific models were merged into a diel multi-tissue metabolic model to predict interactions among the three tissues at the light and dark phases. The metabolic models were also used to analyse the pathways associated with the synthesis of suberin monomers, namely the acyl-lipids, phenylpropanoids, isoprenoids, and flavonoids production. The models developed in this work provide a systematic overview of the metabolism of Q. suber, including its secondary metabolism pathways and cork formation.. 9, 19.\n                            Centre of Biological Engineering, Universidade do Minho, Braga, Portugal."],"submitter_mail":["ecunha@ceb.uminho.pt"],"publication_doi":["10.1371/journal.pcbi.1011499"],"submitter_affiliation":["University of Minho"],"additional_accession":[]},"is_claimable":false,"name":"Cunha2022 - Leaf GSM model of Quercus suber","description":"Genome-scale metabolic model for the leaf of Quercus 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