BioModelsapplication/xmlhttps://www.ebi.ac.uk/biomodels/model/download/MODEL2205040006?filename=DielMultiTissueModel.zipprimaryOK200Emanuel CunhaNon-curatedconstraint-based model*Not Peer Reviewedhttps://www.ebi.ac.uk/biomodels/MODEL2205040006falseBioModelsModelsOtherCunha2022 Diel Multi tissue Model of Quercus suber2021MODEL2205040006Emanuel CunhaEmanuel Cunha, Miguel Silva, Ines Chaves, Huseyin Demirci, Davide Rafael Lagoa, Diogo Lima, Miguel Rocha, Isabel Rocha, Oscar Dias10.1101/2021.03.09.434537, In the last decade, genome-scale metabolic models have been increasingly used to study plant metabolic behavior at the tissue and multi-tissue level under different environmental conditions. Quercus suber, also known as the cork oak tree, is one of the most important forest communities of the Mediterranean/Iberian region. In this work, we present the genome-scale metabolic model of the Q. suber (iEC7871), the first of a woody plant. The metabolic model comprises 7871 genes, 6231 reactions, and 6481 metabolites across eight compartments. Transcriptomics data was integrated into the model to obtain tissue-specific models for the leaf, inner bark, and phellogen, with specific biomass compositions. The tissue-specific models were merged into a diel multi-tissue metabolic model to predict interactions among the three tissues at the light and dark phases. The metabolic models were also used to analyze the pathways associated with the synthesis of suberin monomers. Nevertheless, the models developed in this work can provide insights into other aspects of the metabolism of Q. suber, such as its secondary metabolism and cork formation.. , . 1 Centre of Biological Engineering, Universidade do Minho, 4710-057 Braga, Portugal 2 LABBELS – Associate Laboratory, Braga, Guimarães, Portugal 3 Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 7 Quinta do Marquês, 2780-157 Oeiras, Portugal 4 iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal 5 SnT/University of Luxembourg, Luxembourgecunha@ceb.uminho.pt10.1101/2021.03.09.434537University of MinhoTrees, Cork Oak, Cork Oak Tree, Cork Oak Trees, Cork, Quercus ilex, Holly Oak, Tissue, Quercus infectoria, Oak Tree., simple tissue, Oak Trees, Oak, Holly, Tree, Quercus suber, cork oak, Holly Oaks, Oaks, Oak TreeTrees, Cork Oak, Cork Oak Tree, Cork Oak Trees, Cork, Quercus ilex, Holly Oak, Tissue, Quercus infectoria, Oak Tree., simple tissue, Oak Trees, Oak, Holly, Tree, Quercus suber, cork oak, Holly Oaks, Oaks, Oak TreefalseCunha2022 - Diel Multi-tissue Model of Quercus suberDiel Multi-tissue GSM model of Quercus suber2022-05-042022-05-062022-05-04MODEL2205040006MODEL220504000610.1101/2021.03.09.434537