{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"submitter":["Detlef Weigel"],"organism":["Arabidopsis thaliana"],"software":["MicroArraySuite 5.0"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-AFMX-9"],"description":["The activity of genes and their encoded products can be regulated in several ways, but transcription is the primary level, since all other modes of regulation (RNA splicing, RNA and protein stability, etc.) are dependent on a gene being transcribed in the first place. The importance of transcriptional regulation has been underscored by the recent flood of global expression analyses, which have confirmed that transcriptional co-regulation of genes that act together is the norm, not the exception. Moreover, many studies suggest that evolutionary change is driven in large part by modifications of transcriptional programs. An essential first step toward deciphering the transcriptional code is to determine the expression pattern of all genes. With this goal in mind, an international effort to d"],"repository":["biostudies-arrayexpress"],"sample_protocol":["Nucleic Acid Extraction - Title: Trizol extraction. Description:","Hybridization - Title: Fluidics Station Protocol. Description:","Labeling - Title: Affymetrix in vitro transcription. Description:"],"figure_sub":["MIAME Score","Raw Data","Organization","Assays and Data","Additional Files","MAGE-TAB Files","Array Designs"],"data_protocol":["Feature Extraction - Title: Affymetrix CEL Analysis (Percentile). Description:"],"omics_type":["Metabolomics","Unknown","Transcriptomics","Genomics","Proteomics"],"pubmed_abstract":["Regulatory regions of plant genes tend to be more compact than those of animal genes, but the complement of transcription factors encoded in plant genomes is as large or larger than that found in those of animals. Plants therefore provide an opportunity to study how transcriptional programs control multicellular development. We analyzed global gene expression during development of the reference plant Arabidopsis thaliana in samples covering many stages, from embryogenesis to senescence, and diverse organs. Here, we provide a first analysis of this data set, which is part of the AtGenExpress expression atlas. We observed that the expression levels of transcription factor genes and signal transduction components are similar to those of metabolic genes. Examining the expression patterns of la"],"study_type":["transcription profiling by array"],"species":["Arabidopsis thaliana"],"pubmed_title":["A gene expression map of Arabidopsis thaliana development"],"pubmed_authors":["Markus Schmid","Detlef Weigel","Jan Lohmann","Markus Schmid, Timothy S Davison, Stefan R Henz, Utz J Pape, Monika Demar, Martin Vingron, Bernhard Scholkopf, Detlef Weigel, Jan U Lohmann"],"additional_accession":[]},"is_claimable":false,"name":"Transcription profiling of 80 Arabidopsis tissues/cells (AtGenExpress data) see also E-TABM-17 for a re-annotated set with CEL files for download","description":"The activity of genes and their encoded products can be regulated in several ways, but transcription is the primary level, since all other modes of regulation (RNA splicing, RNA and protein stability, etc.) are dependent on a gene being transcribed in the first place. The importance of transcriptional regulation has been underscored by the recent flood of global expression analyses, which have confirmed that transcriptional co-regulation of genes that act together is the norm, not the exception. Moreover, many studies suggest that evolutionary change is driven in large part by modifications of transcriptional programs. An essential first step toward deciphering the transcriptional code is to determine the expression pattern of all genes. With this goal in mind, an international effort to d","dates":{"release":"2022-11-20T00:00:00Z","modification":"2022-11-20T22:29:44.412Z","creation":"2022-02-03T14:51:29.561Z"},"accession":"E-AFMX-9","cross_references":{"pubmed":["15806101"],"EFO":["EFO_0002768"],"doi":["15806101"]}}