biostudies-arrayexpressHomo sapienshttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-14028Single nuclear RNA sequencing of tissue from BPH patients (n=4) that underwent elective HOLEP surgery. This data was utilised in conjunction with the single nuclear ATAC data of the same tissue to identify open chromatin enrichment peaks that are associated with gene expression, and ultimately to establish an inference with GWAS variants.biostudies-arrayexpressSequencing - Sequencing was performed using NovaSeq6000, 30,000 reads per cells using the cycling conditions described in 10x protocol (CG000338 rev F).Nucleic Acid Extraction - Nucleic acid was extracted using 10x Genomics kit (ATAC+GEM) following the manufacturer's guidelines (CG000338 rev F).Sample Collection - Samples were collected from BPH patients that underwent elective HOLEP surgery.Library Construction - Library construction was created using 10x Genomics kit (ATAC+GEM).MINSEQE ScoreAssays and DataorganisationMAGE-TAB FilesMetabolomicsUnknownTranscriptomicsGenomicsProteomicsN/AIllumina NovaSeq 6000single nucleus RNA sequencingHomo sapiensERP159909Michael NgfalseSingle nuclear RNA sequencing of Benign Prostate Hyperplasia tissueSingle nuclear RNA sequencing of tissue from BPH patients (n=4) that underwent elective HOLEP surgery. This data was utilised in conjunction with the single nuclear ATAC data of the same tissue to identify open chromatin enrichment peaks that are associated with gene expression, and ultimately to establish an inference with GWAS variants.2026-04-07T00:00:00Z2026-04-07T01:00:57.376Z2024-04-26T17:10:21.199ZE-MTAB-14028ERP159909EFO_0002944EFO_0004170EFO_0009809EFO_0005518EFO_0004184