{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown","Transcriptomics","Genomics","Proteomics"],"submitter":["Fazio Grazia"],"instrument_platform":["NextSeq 550"],"study_type":["DNA-seq"],"organism":["Homo sapiens"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-14362"],"description":["Pediatric patients affected by B-cell precursor ALL and enrolled in the AIEOP-BFM treatment protocol in Italian centers were analysed at diagnosis for mutations in cohesin genes. The experiment was performed designing a custom panel of 40 genes involved in leukaemia (IDT probe)."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Library Construction - For library preparation we used the Illumina Nextera Flex for Enrichment protocol","Nucleic Acid Extraction - DNA was extracted from cell pellets using the Promega kit Wizard® SV Genomic DNA Purification Systems","Sequencing - The NGS run has been performed on NexSeq550 Illumina platform, 2x150","Sample Collection - Mononuclear cell by ficoll density purification of Bone Marrow or Peripheral Blood"],"figure_sub":["Organization","MINSEQE Score","Assays and Data","MAGE-TAB Files"],"pubmed_authors":["Fazio Grazia"],"additional_accession":[]},"is_claimable":false,"name":"Pediatric BCP-ALL analysis by DNA Target Capture NGS panel","description":"Pediatric patients affected by B-cell precursor ALL and enrolled in the AIEOP-BFM treatment protocol in Italian centers were analysed at diagnosis for mutations in cohesin genes. The experiment was performed designing a custom panel of 40 genes involved in leukaemia (IDT probe).","dates":{"release":"2025-08-31T00:00:00Z","modification":"2025-08-31T01:02:25.47Z","creation":"2024-08-13T11:59:43.42Z"},"accession":"E-MTAB-14362","cross_references":{"ENA":["ERP163229"],"EFO":["EFO_0002944","EFO_0004170","EFO_0002693","EFO_0005518","EFO_0004184"]}}