{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown","Transcriptomics","Genomics","Proteomics"],"submitter":["Andreas Zietzer"],"instrument_platform":["Illumina NovaSeq 6000"],"study_type":["microRNA profiling by high throughput sequencing"],"organism":["Homo sapiens"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-14837"],"description":["Human citrate Plasma was collected from the left atrial appendage directly after catheter ablation for atrial fibrillation with either teh Boston Scientific Cryo-Balloon System or the Boston Scientific Pulsed Field Ablation System.  A total of 154 microRNAs (miRs) were consistently detected across all samples. While some variability in miR expression levels was observed, no statistically significant differences were found after adjusting for multiple comparisons."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Sample Collection - Human citrate Plasma was collected from the left atrial appendage directly after catheter ablation for atrial fibrillation with either teh Boston Scientific Cryo-Balloon System or the Boston Scientific Pulsed Field Ablation System.","Library Construction - Small RNA sequencing was performed with library preparation using the NEXTFLEX® Small RNA-Seq Kit v4.","Sample Treatment - Platelet free citrate plasma from the left atrium after plused field ablation vs cryo balloon ablation for atrial fibrillation","Nucleic Acid Extraction - RNA was extracted from human plasma using the miRNeasy Serum/Plasma Kit (Qiagen)","Sequencing - Sequencing was carried out on a NovaSeq 6000 platform with 1x50bp read lengths."],"figure_sub":["Organization","MINSEQE Score","Assays and Data","MAGE-TAB Files"],"pubmed_authors":["Andreas Zietzer"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of microRNA expression after AF-Ablation with Cryo balloon vs. Pulsed field ablation","description":"Human citrate Plasma was collected from the left atrial appendage directly after catheter ablation for atrial fibrillation with either teh Boston Scientific Cryo-Balloon System or the Boston Scientific Pulsed Field Ablation System.  A total of 154 microRNAs (miRs) were consistently detected across all samples. While some variability in miR expression levels was observed, no statistically significant differences were found after adjusting for multiple comparisons.","dates":{"release":"2025-12-31T00:00:00Z","modification":"2025-12-31T02:02:15.17Z","creation":"2025-02-14T10:32:34.384Z"},"accession":"E-MTAB-14837","cross_references":{"ENA":["ERP169233"],"EFO":["EFO_0002944","EFO_0004170","EFO_0002896","EFO_0005518","EFO_0004184","EFO_0003969"]}}