{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"submitter":["Matteo Zanovello"],"organism":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-15564"],"description":["We performed RNA-seq on HeLa cells to assess the shared transcriptomics changes between USP10 and TDP-43 overexpression, as well as to understand the effect of USP10 overexpression on TDP-43 loss-of-function targets."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Library Construction - KAPA polyA","Sample Treatment - OE using viral vectors, KD using siRNA","Sample Collection - scraping from plate","Sequencing - Illumina-seq","Nucleic Acid Extraction - RNeasy mini (QIAgen)","Growth Protocol - cell culture for 10 days, changing media every 72 hours"],"figure_sub":["Organization","MINSEQE Score","Assays and Data","MAGE-TAB Files"],"data_protocol":["Data Transformation - Salmon + DESeq2","Sequence Alignment - STAR"],"omics_type":["Unknown","Transcriptomics","Genomics","Proteomics"],"instrument_platform":["Illumina NovaSeq 6000"],"study_type":["RNA-seq of coding RNA"],"species":["Homo sapiens"],"pubmed_authors":["Matteo Zanovello"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq from USP10 and TDP-43 overexpression and TDP-43 knockdown associated with or without USP10 overexpression in HeLa cells","description":"We performed RNA-seq on HeLa cells to assess the shared transcriptomics changes between USP10 and TDP-43 overexpression, as well as to understand the effect of USP10 overexpression on TDP-43 loss-of-function targets.","dates":{"release":"2025-09-21T00:00:00Z","modification":"2025-09-21T01:04:17.948Z","creation":"2025-09-08T11:16:51.587Z"},"accession":"E-MTAB-15564","cross_references":{"ENA":["ERP179764"],"EFO":["EFO_0002944","EFO_0004170","EFO_0003789","EFO_0004917","EFO_0005518","EFO_0003816","EFO_0003738","EFO_0004184","EFO_0003969"]}}