{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"omics_type":["Metabolomics","Unknown","Transcriptomics","Genomics","Proteomics"],"submitter":["helen Parker"],"instrument_platform":["Illumina NovaSeq 6000"],"study_type":["DNA-seq"],"organism":["Homo sapiens"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-15600"],"description":["High genomic complexity (HGC) is linked to poor prognosis in chronic lymphocytic leukaemia (CLL), but its independent prognostic value remains uncertain amid emerging biomarkers. Therefore we analysed copy number alterations in 495 treatment-naïve patients from three randomized trials (CLL4, ADMIRE, ARCTIC), incorporating IGHV status, telomere length (TL), targeted sequencing, and DNA-methylation subtypes."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Sample Collection - Peripheral blood mononuclear cell samples via venipuncture","Library Construction - Agilent SureSelect QXT whole genome library preparation kit","Nucleic Acid Extraction - Qiagne DNeasy column extraction","Sequencing - Illumina NovaSeq 6000 sequencer"],"figure_sub":["Organization","MINSEQE Score","Assays and Data","MAGE-TAB Files"],"pubmed_authors":["helen Parker"],"additional_accession":[]},"is_claimable":false,"name":"Copy number profiling of CLL patient samples","description":"High genomic complexity (HGC) is linked to poor prognosis in chronic lymphocytic leukaemia (CLL), but its independent prognostic value remains uncertain amid emerging biomarkers. Therefore we analysed copy number alterations in 495 treatment-naïve patients from three randomized trials (CLL4, ADMIRE, ARCTIC), incorporating IGHV status, telomere length (TL), targeted sequencing, and DNA-methylation subtypes.","dates":{"release":"2026-04-01T00:00:00Z","modification":"2026-04-02T01:05:03.855Z","creation":"2025-09-17T21:43:53.847Z"},"accession":"E-MTAB-15600","cross_references":{"ENA":["ERP180258"],"EFO":["EFO_0002944","EFO_0004170","EFO_0002693","EFO_0005518","EFO_0004184"]}}