biostudies-arrayexpressUnknownTranscriptomicsGenomicsProteomicsFlorent KempfIllumina HiSeq 4000RNA-seq of coding RNAGallus gallusGallus gallushttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-16061Early life gut microbiota plays a critical role in gut development, maturation of the immune response and protection against enteric pathogens such as Salmonella. In this study, we investigated how different gut microbiota compositions influence the host transcriptomic signatures and susceptibility to Salmonella infection in chicks.biostudies-arrayexpressSample Collection - During the experimental infection experiment, we have performed the following collections: Collection of the spleen to be placed in RNAlater Collection of a tonsil to be placed in RNAlaterSequencing - Please contact the Genoa platform (Nantes, France)Nucleic Acid Extraction - Microbial DNA was extracted using the NucleoMag DNA Microbiome kit (4 × 96 preps), following the manufacturer’s instructions (MACHEREY-NAGEL, France)Library Construction - Please contact the Genoa platform (Nantes, France)OrganizationMINSEQE ScoreAssays and DataMAGE-TAB FilesFlorent KempffalseGut microbiome composition and host transcriptome responses in chick Salmonella infectionEarly life gut microbiota plays a critical role in gut development, maturation of the immune response and protection against enteric pathogens such as Salmonella. In this study, we investigated how different gut microbiota compositions influence the host transcriptomic signatures and susceptibility to Salmonella infection in chicks.2025-11-30T00:00:00Z2025-11-30T02:02:29.506Z2025-11-13T15:01:58.768ZE-MTAB-16061ERP184137EFO_0002944EFO_0004170EFO_0005518EFO_0003738EFO_0004184