biostudies-arrayexpressViviane BalloyHomo sapienshttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-16714To identify PI3K pathway-related genes that may contribute to BECs antifungal activity, we performed a transcriptomic profiling of BECs incubated or not with LY294002, a PI3K inhibitor, and infected with A. fumigatus for 0, 2 and 4 h.biostudies-arrayexpressSample Collection - RNA extraction was from BEAS-2B cells infected with A. fumigatus and incubated or not with PI3 kinase inhibitor for 0, 2 and 4 hoursSequencing - Single-end sequencing was performed on HiSeq 2000 sequencer (Illumina)Library Construction - library construction using the TruSeq RNA Sample Prep Kit v2 (Illumina, #RS-122-2001 and #RS-122-2002, San Diego, CA) according to the manufacturer’s instructionsNucleic Acid Extraction - RNA were extracted using NucleoSpin RNAII® kit (Macherey-Nagel, Düren, Germany)OrganizationMINSEQE ScoreAssays and DataProcessed DataMAGE-TAB FilesData Transformation - Data were normalized using DESeq2 and the default parameters.MetabolomicsUnknownTranscriptomicsGenomicsProteomicsIllumina HiSeq 2000RNA-seq of coding RNAHomo sapiensViviane BalloyfalseTranscriptome of BEAS-2B cells infected with Aspergillus fumigates in presence or not of PI3 kinase inhibitorTo identify PI3K pathway-related genes that may contribute to BECs antifungal activity, we performed a transcriptomic profiling of BECs incubated or not with LY294002, a PI3K inhibitor, and infected with A. fumigatus for 0, 2 and 4 h.2026-06-28T00:00:00Z2026-06-28T01:00:46.7Z2026-03-03T12:03:19.003ZE-MTAB-16714ERP189828EFO_0002944EFO_0004170EFO_0005518EFO_0003816EFO_0003738EFO_0004184