{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown","Transcriptomics","Genomics","Proteomics"],"submitter":["Michael Scherer"],"study_type":["methylation profiling by array"],"organism":["Homo sapiens"],"species":["Homo sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-16743"],"description":["DNA extracted from human A549 cell lines and a mouse cell line established from a KPC (KrasG12D/+/p53 fl/fl/LSL- Rosa26LSL-Cas9-EGFP)  tumor mouse model. We mixed eight different fractions (0/100, 15/85, 30/70, 45/55, 60/40, 75/25, 90/10, and 100/0) of human and mouse DNA. The mixture was hybridized on the Illumina Infinium EPICv2 BeadArray at the Microarray Core Facility of the German Cancer Research Center."],"repository":["biostudies-arrayexpress"],"sample_protocol":["Sample Collection - A549 cell lines were purchased. The KPC cell line was established from a published mouse model (DuPage et al, Nat Protoc., 2009).","Hybridization - Hybridization was performed according to the manufacturers (Illumina's) instructions at the Micorarray Core Facility at the German Cancer Research Center","Scaning - Array screening was performed according to the manufacturers (Illumina's) instructions at the Micorarray Core Facility at the German Cancer Research Center","Nucleic Acid Extraction - DNA was extracted using the Qiagen AllPrep DNA/RNA Mini Kit.","Labeling - Bisulfite conversion was performed using the EZ DNA Methylation™ kit from Zymo Research."],"figure_sub":["MIAME Score","Raw Data","Organization","Assays and Data","MAGE-TAB Files","Array Designs"],"pubmed_authors":["Michael Scherer"],"additional_accession":[]},"is_claimable":false,"name":"Artificial mixtures of human and mouse DNA profiled on the Illumina Infinium EPICv2 BeadArray","description":"DNA extracted from human A549 cell lines and a mouse cell line established from a KPC (KrasG12D/+/p53 fl/fl/LSL- Rosa26LSL-Cas9-EGFP)  tumor mouse model. We mixed eight different fractions (0/100, 15/85, 30/70, 45/55, 60/40, 75/25, 90/10, and 100/0) of human and mouse DNA. The mixture was hybridized on the Illumina Infinium EPICv2 BeadArray at the Microarray Core Facility of the German Cancer Research Center.","dates":{"release":"2026-03-16T00:00:00Z","modification":"2026-03-16T08:34:09.406Z","creation":"2026-03-11T15:38:34.38Z"},"accession":"E-MTAB-16743","cross_references":{"EFO":["EFO_0002944","EFO_0003814","EFO_0003813","EFO_0002759","EFO_0005518","EFO_0003815"]}}