biostudies-arrayexpressAlan MackayHomo sapienshttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-16762Methylation array based profiling of paediatric diffuse type high grade glioma primary tumours and patient derived orthotropic xenografts (PDX) in mice.biostudies-arrayexpressHybridization - Array Hybridisation ProtocolNucleic Acid Extraction - DNA was extracted from 6 micron sections of FFPE material using the Qiagen DNAeasy kit according to manufacturers instructionsScaning - Methylation arrays were scanned using Illumina iScan microarray scanner. After QC results were exported as standard idat files.Labeling - Nucleic acid Labelling was performed using Illuminas methylation array kit as described by the manufacturerSample Collection - Samples were collected as either surgical specimens or patient derived orthotropic xenografts in nude miceMIAME ScoreRaw DataOrganizationAssays and DataMAGE-TAB FilesArray DesignsUnknownTranscriptomicsGenomicsProteomicsIllumina Hybridisation OvenIllumina iScanmethylation profiling by arrayHomo sapiensCharacterisation of patient-derived site-specific in vivo models of paediatric-type diffuse high-grade glioma (PDHGG) using magnetic resonance imagingAlan MackayJessica K. R. Boult, Diana M. Carvalho, Ketty Kessler, Valeria Molinari, Alan Mackay, Yura Grabovska, Mariama Fofana, Kathryn R. Taylor, Lynn Bjerke, Elisabet Fernandez, Rita Pereira, Matthew Clarke, Sara Temelso, Anna Burford, Drenusha Sejdiu, Angel M. Carcaboso, Julia V. Cockle, Fernando Carceller, Lynley V. Marshall, Sucheta Vaidya, Leslie Bridges, Navneet Singh, Simon Stapleton, Samantha Hettige, Safa Al-Sarraj, Zita Reisz, Bassel Zebian, Cristina Bleil, Timothy EG Hassall, Angela Mastronuzzi, Andrea Carai, Philip Benjamin, G. Stefania Colafati, Maria Vinci, Chris Jones, Simon P. RobinsonfalseIllumina Infinium HumanMethylation EPIC Profiling of paediatric diffuse type high grade gliomas and patient derived xenograftsMethylation array based profiling of paediatric diffuse type high grade glioma primary tumours and patient derived orthotropic xenografts (PDX) in mice.2026-03-31T00:00:00Z2026-03-31T01:03:47.126Z2026-03-17T12:58:38.697ZE-MTAB-16762E-MTAB-16763EFO_0002944EFO_0003814EFO_0003813EFO_0002759EFO_0005518EFO_0003815