biostudies-arrayexpressMetabolomicsUnknownTranscriptomicsGenomicsProteomicsKristian Almstrupmethylation profiling by arrayHomo sapiensHomo sapienshttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-17259The Copenhagen Analgesic Study (COPANA) (ClinicalTrials.gov ID: NCT04369222) is a single-center, prospective, observational pregnancy and birth cohort from Copenhagen University Hospital - Rigshospitalet, Denmark. This data represents blood DNA methylation analysis of the children using Illumina EPICv2 beadarrays. The infants are divided into groups depending on: Paternal use of paracetamol / Maternal use of paracetamol / Maternal use of fungizides Pattern Group 0/0/0 A 0/0/1 B 0/0/NA C 0/1/0 D 0/1/1 E 0/1/NA F 1/0/0 G 1/0/1 H 1/0/NA I 1/1/0 J 1/1/1 K 1/1/NA L NA/0/0 M NA/0/1 N NA/1/0 O NA/1/1 P NA/1/NA Q Where 1 implies exposure, 0 implies no exposure, and NA implies not available.biostudies-arrayexpressNucleic Acid Extraction - DNA was purified from infant blood samples using the automated Maxwell 16 system (SEV AS1010, Promaga, Madison, WI, USA) and quantified by NanoDrop (Life Technologies Europe BV, Naerum, Denmark).Labeling - Bisulfite-treatment of DNA according to Illumina standard protocols.Scaning - Illumina iScan system, and probe intensities extracted in GenomeStudioHybridization - Illumina standard protocols following the manufacturer's recommendations.Sample Collection - At three months postpartum, blood samples were obtained from infantsMIAME ScoreRaw DataOrganizationAssays and DataProcessed DataMAGE-TAB FilesArray DesignsKristian AlmstrupData Transformation - Data were processed with the minfi R package and normalised using Subset-quantile Within Array Normalisation, and probes containing SNPs in the CpG or extension sites were removed.falseCOPAPA DNA methylationThe Copenhagen Analgesic Study (COPANA) (ClinicalTrials.gov ID: NCT04369222) is a single-center, prospective, observational pregnancy and birth cohort from Copenhagen University Hospital - Rigshospitalet, Denmark. This data represents blood DNA methylation analysis of the children using Illumina EPICv2 beadarrays. The infants are divided into groups depending on: Paternal use of paracetamol / Maternal use of paracetamol / Maternal use of fungizides Pattern Group 0/0/0 A 0/0/1 B 0/0/NA C 0/1/0 D 0/1/1 E 0/1/NA F 1/0/0 G 1/0/1 H 1/0/NA I 1/1/0 J 1/1/1 K 1/1/NA L NA/0/0 M NA/0/1 N NA/1/0 O NA/1/1 P NA/1/NA Q Where 1 implies exposure, 0 implies no exposure, and NA implies not available.2026-06-26T00:00:00Z2026-06-26T01:01:10.113Z2026-06-23T20:11:02.454ZE-MTAB-17259EFO_0002944EFO_0003814EFO_0003813EFO_0002759EFO_0005518EFO_0003816EFO_0003815