{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"submitter":["Shen Lian"],"organism":["C57BL/6J"],"software":["SAM 2.2"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-MTAB-2587"],"description":["To identify novel transcriptional factors involved in dysfunctional hepatic lipids homeostasis in obesity"],"repository":["biostudies-arrayexpress"],"sample_protocol":["Sample Treatment - Mice were sacrificed at 16:00 (Zeitgeber Time 8 during light phase).","Labeling - Equal aliquots of total RNA from each of four mouse livers in each group were pooled and used for biotin labeling as described in the Affymetrix technical bulletin.","Nucleic Acid Extraction - Total RNA was prepared from each liver using TRIzol.","Hybridization - The resulting RNA was used to hybridize GeneChips (Affymetrix) according to the manufacturer’s protocols."],"figure_sub":["MIAME Score","Organization","Assays and Data","MAGE-TAB Files","Array Designs"],"data_protocol":["Data Transformation - Significance analysis of microarrays (SAM) was used to identify differences between different samples."],"omics_type":["Metabolomics","Unknown","Transcriptomics","Genomics","Proteomics"],"study_type":["transcription profiling by array"],"species":["C57BL/6J"],"pubmed_title":["Hepatic differentiated embryo-chondrocyte expressed gene 1 (DEC1) inhibits sterol regulatory element-binding protein-1c (SREBP-1c) expression and alleviates fatty liver phenotype"],"pubmed_authors":["Lian Shen, Anfang Cui, Yuan Xue, Ying Cui, Xueyu Dong, Yong Gao, Hao Yang, Fude Fang, and Yongsheng Chang1","Yongsheng Chang","Shen Lian"],"additional_accession":[]},"is_claimable":false,"name":"ob mice vs wild type c57 mRNA","description":"To identify novel transcriptional factors involved in dysfunctional hepatic lipids homeostasis in obesity","dates":{"release":"2014-05-09T00:00:00Z","modification":"2022-03-14T18:39:07.396Z","creation":"2022-03-14T18:39:07.396Z"},"accession":"E-MTAB-2587","cross_references":{"EFO":["EFO_0002768","EFO_0002944","EFO_0003813","EFO_0003816","EFO_0003969","EFO_0003815"]}}