biostudies-arrayexpressShen LianC57BL/6JSAM 2.2https://www.ebi.ac.uk/biostudies/studies/E-MTAB-2587To identify novel transcriptional factors involved in dysfunctional hepatic lipids homeostasis in obesitybiostudies-arrayexpressSample Treatment - Mice were sacrificed at 16:00 (Zeitgeber Time 8 during light phase).Labeling - Equal aliquots of total RNA from each of four mouse livers in each group were pooled and used for biotin labeling as described in the Affymetrix technical bulletin.Nucleic Acid Extraction - Total RNA was prepared from each liver using TRIzol.Hybridization - The resulting RNA was used to hybridize GeneChips (Affymetrix) according to the manufacturer’s protocols.MIAME ScoreOrganizationAssays and DataMAGE-TAB FilesArray DesignsData Transformation - Significance analysis of microarrays (SAM) was used to identify differences between different samples.MetabolomicsUnknownTranscriptomicsGenomicsProteomicstranscription profiling by arrayC57BL/6JHepatic differentiated embryo-chondrocyte expressed gene 1 (DEC1) inhibits sterol regulatory element-binding protein-1c (SREBP-1c) expression and alleviates fatty liver phenotypeLian Shen, Anfang Cui, Yuan Xue, Ying Cui, Xueyu Dong, Yong Gao, Hao Yang, Fude Fang, and Yongsheng Chang1Yongsheng ChangShen Lianfalseob mice vs wild type c57 mRNATo identify novel transcriptional factors involved in dysfunctional hepatic lipids homeostasis in obesity2014-05-09T00:00:00Z2022-03-14T18:39:07.396Z2022-03-14T18:39:07.396ZE-MTAB-2587EFO_0002768EFO_0002944EFO_0003813EFO_0003816EFO_0003969EFO_0003815