biostudies-arrayexpressRichard ClarkArabidopsis lyratahttps://www.ebi.ac.uk/biostudies/studies/E-MTAB-5072Illumina, strand-specific RNA sequencing of A lyrata for gene annotation.biostudies-arrayexpressSequencing - Illumina Genome Analyzer IIxOrganizationMINSEQE ScoreAssays and DataMAGE-TAB FilesMetabolomicsUnknownTranscriptomicsGenomicsProteomicsIllumina Genome Analyzer IIxDespite the central importance of noncoding DNA to gene regulation and evolution, understanding of the extent of selection on plant noncoding DNA remains limited compared to that of other organisms. Here we report sequencing of genomes from three Brassicaceae species (Leavenworthia alabamica, Sisymbrium irio and Aethionema arabicum) and their joint analysis with six previously sequenced crucifer genomes. Conservation across orthologous bases suggests that at least 17% of the Arabidopsis thaliana genome is under selection, with nearly one-quarter of the sequence under selection lying outside of coding regions. Much of this sequence can be localized to approximately 90,000 conserved noncoding sequences (CNSs) that show evidence of transcriptional and post-transcriptional regulation. PopulatiRNA-seq of coding RNAArabidopsis lyrataAn atlas of over 90,000 conserved noncoding sequences provides insight into crucifer regulatory regionsRichard ClarkMathieu BlanchetteHaudry A, Platts AE, Vello E, Hoen DR, Leclercq M, Williamson RJ, Forczek E, Joly-Lopez Z, Steffen JG, Hazzouri KM, Dewar K, Stinchcombe JR, Schoen DJ, Wang X, Schmutz J, Town CD, Edger PP, Pires JC, Schumaker KS, Jarvis DE, Mandáková T, Lysak MA, van den Bergh E, Schranz ME, Harrison PM, Moses AM, Bureau TE, Wright SI, Blanchette MfalseArabidopsis lyrata strain:MN47 Transcriptome or Gene expressionIllumina, strand-specific RNA sequencing of A lyrata for gene annotation.2013-06-26T00:00:00Z2022-02-04T06:52:34.277Z2022-02-04T06:52:34.277ZE-MTAB-507223817568SRP024292EFO_0004170EFO_000373810.1038/ng.2684