{"database":"biostudies-arrayexpress","file_versions":[],"scores":null,"additional":{"omics_type":["Metabolomics","Unknown","Transcriptomics","Genomics","Proteomics"],"submitter":["Martin Chalfie"],"pubmed_abstract":["The extent of gene regulation in cell differentiation is poorly understood. We previously used saturation mutagenesis to identify 18 genes that are needed for the development and function of a single type of sensory neuron--the touch receptor neuron for gentle touch in Caenorhabditis elegans. One of these genes, mec-3, encodes a transcription factor that controls touch receptor differentiation. By culturing and isolating wild-type and mec-3 mutant cells from embryos and applying their amplified RNA to DNA microarrays, here we have identified genes that are known to be expressed in touch receptors, a previously uncloned gene (mec-17) that is needed for maintaining touch receptor differentiation, and more than 50 previously unknown mec-3-dependent genes. These genes are randomly distributed "],"study_type":["transcription profiling by array"],"organism":["Caenorhabditis elegans"],"species":["Caenorhabditis elegans"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/E-SMDB-1461"],"repository":["biostudies-arrayexpress"],"pubmed_title":["Identification of genes expressed in C. elegans touch receptor neurons."],"figure_sub":["MIAME Score","Raw Data","Organization","Assays and Data","MAGE-TAB Files","Array Designs"],"pubmed_authors":["Tina Boussard","Martin Chalfie","Zhang Y, Ma C, Delohery T, Nasipak B, Foat BC, Bounoutas A, Bussemaker HJ, Kim SK, Chalfie M"],"additional_accession":[]},"is_claimable":false,"name":"Transcription profiling of C. elegans neurons","description":null,"dates":{"release":"2005-07-13T00:00:00Z","modification":"2022-02-04T03:56:09.78Z","creation":"2022-02-04T03:56:09.78Z"},"accession":"E-SMDB-1461","cross_references":{"pubmed":["12124626"],"EFO":["EFO_0002768"],"doi":["12124626"]}}